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The BP-lowering effects of sildenafil did not differ significantly in the normotensive and hypertensive men. Age significantly affected the BP reductions; decreases in SBP, DBP, and mean arterial pressure were greater in men 49 years old and older than in those younger than 49 years old. How it works. Sildenafil may be used to treat erectile dysfunction (ED or impotence) in men You can take Viagra (sildenafil) if you have high blood pressure that is controlled by blood pressure medications. Viagra (sildenafil) works by blocking an enzyme called PDE-5, which, in turn, prevents the break down of another substance called cGMP, which causes smooth muscle to relax and dilate. Taking sildenafil with a nitrate medicine can cause a sudden and serious decrease in blood pressure. To make sure sildenafil is safe for you, tell your doctor if you have ever had: heart problems (chest pain, a heart rhythm disorder, heart attack); high or low blood pressure; blood circulation problems; does viagra raise blood pressure have low blood pressure, or high blood pressure that is not controlled; have a deformed penis shape; have had an erection that lasted for more than 4 hours; have problems with your blood cells such as sickle cell anemia, multiple myeloma, or leukemia; have retinitis pigmentosa, a rare genetic (runs in families) eye disease

Taking sildenafil (Viagra) with certain medications, such as alpha blockers, medications for high blood pressure, or ritonavir (Norvir) can cause your blood pressure to drop too low. If you take any of these medications, talk with your provider to see if sildenafil (Viagra) is safe for you. Studies in healthy volunteers show that a single dose of Viagra lowers systolic blood pressure by about 8 mmHg and diastolic pressure by about 5 mmHg. You should tell your doctor if you have high or low blood pressure before starting Viagra. Taking sildenafil with a nitrate medicine can cause a sudden and serious decrease in blood pressure. Contact your doctor or seek emergency medical attention if your erection is painful or lasts longer than 4 hours. A prolonged erection (priapism) can damage the penis. Stop using Viagra and get emergency medical help if you have sudden vision loss.